Endocrine Abstracts

Introduction: Monogenic diabetes is a rare type of diabetes that should be evoked in the presence of associated features. Here we report a female patient with complete phenotype of MODY5 while discussing its possible complications.Case report: A.B was 35-year-old patient with a rich family history of diabetes and renal cysts. Sha had a personal medical history of Diabetes since the age of 23 years, on basal bolus insulin regimen, recurrent episodes of ur...

Introduction: Hypoparathyroidism (HypoPT) is a rare endocrine disease characterized by abnormally low concentrations of PTH resulting in hypocalcemia. Etiologies are various and are dominated by postoperative HypoPT. HypoPT needs a lifelong treatment and follow-up in order to maintain appropriate calcium levels and prevent chronic complications.Patients and Methods: A retrospective descriptive study was conducted at the endocrinology department in Fattou...

Introduction : Primary adrenal lymphomas (PAL) are extremely rare and constitute 0.5% of all adrenal tumors. The number of cases described is approximately 70 cases [1] and It is bilaterally manifested in approximately 70% of cases [2]. The diagnosis is made on histological features, as there is no specific symptoms. Treatement is based on chemotherapy and prognosis is usually poor. We report two cases of bilateral PAL.Cases: First case: A 63-year-old wo...

Introduction: Adrenocortical carcinoma is a very rare tumor with a heterogenous prognosis.Case report: Patient R.B is a 58-year-old female patient with no particular familial history. She had a personal history of hypertension, discovered 6 months ago well controlled with beta blockers and amlodipine. Two weeks before her admission to the hospital, she reported having constantly worsening abdominal pain followed by frequent vomiting few days later. The p...

Introduction: Pheochromocytoma is a rare tumour of the adrenal medulla. The aim of our work is to describe the clinical, biological and anatomopathological profile of pheochromocytomas.Material and method: Retrospective descriptive study carried out in the endocrinology department of the Fattouma Bourguiba University Hospital, Monastir, Tunisia.Results: Analysis of a series of 13 cases found 9 women and 4 men with an average age of...

Objectives: The aim of our work is to evaluate the prevalence of cardiovascular risk factors in type 1 diabetics aged between 10 and 20 years.Patients and methods: Retrospective study including 54 type 1 diabetic patients, followed at the endocrinology department of Fatouma Bourguiba hospital of Monastir during the year 2023.Results: The mean age was 34.3 ±1.33 years with a female predominance (sex ratio=F/H) =2. they were all...

Introduction: Insulinoma is a rare neuroendocrine tumor. Its diagnosis is clinico-biological. Preoperative topographical diagnosis is necessary to guide the therapeutic procedure.Observation: We report the case of a 37-year-old patient, without notable pathological history, who was admitted for exploration of severe hypoglycemia, not felt, evolving for 2 years and complicated by convulsive attacks. The initial etiological investigation revealed corticotr...

Introduction: Graves’ disease is a frequent endocrine disorder, often treated as first-line therapy with antithyroid drugs. Herin, we report two female patients with Methimazole allergy while detailing its management.Case Reports: TWO female patients aged respectively 27 and 28 years old were diagnosed with Graves’ disease (GD), diagnosed given the association of peripheral hyperthyroidism and elevated anti TSH receptor antibodies. The first de...

Introduction: Hashimoto’s thyroiditis (HT) is one of the most frequent endocrine diseases worldwide that is typically irreversible. Herein we report the case of a woman who had spontaneous remission of hypothyroidism while discussing the potential mechanisms underlying this unusual evolution.Case report: T.C. is a 44-year-old woman with no familial history of thyroid diseases nor auto-immune conditions. She has no particular personal medical history...

Introduction: The management of prolactinomas, whatever their size, is based on medical treatment with dopamine agonists (DA). The latter allows clinical improvement with efficient control of prolactin secretion and tumor growth. Pituitary surgery or radiotherapy are adjuvant therapies in case of neurologic complication or lack of response to DA.Patients and methods: We conducted a monocentric analytic study of patients followed for confirmed prolactinom...